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doi: 10.3390/biom10091306 152 AbreuHCancianiERaineriDCappellanoGRimondiniLChiocchettiA

Inadequate secretion of intrinsic factor, resulting from lesions that destroy the gastric mucosa (which can be caused by ingestion of corrosives, extensive tumors, and conditions associated with gastric atrophy, such as multiple sclerosis, certain endocrine disorders, iron deficiency, and subtotal gastrectomy) Structural lesions leading to vitamin B 12 deficiency, including regional ileitis, ileal reactions, and malignancies Competition for vitamin B 12 by intestinal parasites or bacteria

The present work was undertaken to characterize further the structural features of the tripeptide which are necessary for the activation of the GSH-receptor

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